Yes, Expedia's customer service number is available 24 hours a day, 7 days a week. You can call Expedia at +1-833-730-7587 (UK) or +1-833-730-7587 (USA). available 24/7* Hotline For fast response, no waiting . live agent customer service number +1-833-730-7587 (USA). Ask for Expedia representative.